Modular Lab Standard

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Modular Lab Standard

automated-synthesizer nuclear-medicine

PRODUCT DESCRIPTION

Positron emission tomography (PET) is widely used for a variety of applications involving radioisotope techniques. The use of our fully automated radiosynthesis device Modular-Lab Standard significantly increases synthesis yields and reduces radiation exposure of the operator to a minimum when labeling 68Ga-DOTA conjugated peptides.

Project Details

As the first system of the Modular-Lab family, Modular-Lab Standard has been specifically designed to allow versatile radiochemical development and production. The system enables custom synthesis processes to be assembled from a set of unit operation modules.
The use of multiple, replaceable modules allow Modular-Lab Standard to be used for various isotopes and many types of reactions. Due to its multifunctionality Modular-Lab Standard can replace several single-purpose devices, which significantly reduces cost and lab space. The included Modular-Lab software provides an intuitive graphical interface, used to design and control the synthesis process.

Advantages

Modular-Lab Standard’s unique modular approach combines the speed and safety of a remote, fully automated system with the flexibility to configure syntheses for novel tracers. Cleaning and sanitation routines can be programmed to take place between runs or overnight. With this multifunctionality, Modular-Lab Standard supports research as well as routine production. Disposable components such as valves, tubing, cartridges and others are standard, off-the-shelf units and can be exchanged as needed for different applications. Modular-Lab Standard can be applied to a wide range of compounds and isotopes. The modules can be arranged to fit even very small hot cells.

Versatility

Available modules include a Peltier/Heater reaction system with solid-state temperature control from -20 °C to +150 °C/ 220 °C, a wide variety of valve modules, instruments for temperature, pressure and radiation detection, a compact semi-preparative HPLC module, analytical HPLC, TLC modules, and many others. The intuitive user interface is easy to program by drag and drop of graphical symbols and adheres to today’s regulatory requirements. Parameters such as temperature, activity, UV detector readings, flow rates, or valve settings can be monitored easily in one window. Reports containing all relevant data and information are created automatically after each run.

Safety Functions

Reliable, automated synthesis with remote monitoring provided as necessary through the graphical computer interface, eliminates the need for hands-on operation and significantly reduces radiation exposure to lab personnel.

Application Examples

We offer a variety of chemical reactions including customized synthesis processes according to your needs, e.g. [18F]FEC, [18F]FDG, [18F]Fluoroethyltyrosine, [18F]Flumazenil, [18F]MISO, [11C]Choline, [11C]Methyl Iodide, [131I]MIBG, 68Ga-DOTA peptides, 64Cu applications, customized syntheses.

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