AR-2000
PRODUCT DESCRIPTION
The AR-2000 imaging scanner is the industry ‘GoldStandard’ for analyzing the purity of [18F]FDG and other PET radiopharmaceuticals, 3H, 14C and alpha emitters on TLC plates, strips, gels, and blots.Project Details
AR-2000 radio-TLC Imaging Scanner
The AR-2000 radio-TLC Imaging Scanner has become the industry ‘Gold Standard’ in the detection of radiolabeled compounds in TLC plates and also in the purity analysis of [18F]FDG. The system provides direct digital counting of all radioisotopes, including high-energy positron emitters and low energy betas, such as tritium [3H], without the need to exchange detectors.
Key Features
- Easy-to-use software WinScan (standard) or RaPET-Lab/AR (optional)
- RaPET-Lab/AR software to support GMP compliance of the process
- Excellent spatial resolution
- High sensitivity for all radioisotopes
- Fast, automated and reliable runs
- Minimized technician exposure and bench time
Technology
The AR-2000 Imaging Scanner is the industry ‘Gold Standard’ for analyzing the purity of [18F]FDG and other PET radiopharmaceuticals and detecting 3H ,14C and alpha emitters on TLC plates, strips, gels and blots. The system provides direct digital counting of all radioisotopes including positron emitters, which guarantees quantitative accuracy and reproducibility for important metabolism experiments and radiochemical purity measurements. The AR-2000 is linear over 4-5 decades of activity, a range 100 – 1,000 times greater than the linear range of X-ray film, providing fast and reliable analyses. The scanner uses a gas-filled proportional counter, which can detect all beta and gamma emitting isotopes. An entire TLC lane can be imaged in less than one minute. Multiple lanes can be analyzed in a single automated run without operator intervention.
Applications
PET / Nuclear Medicine:
Fast, accurate results for SPECT or PET radiopharmaceutical compounds labeled with 68Ga, 18F, 11C, 99mTc, 111In, etc. Very useful for radiopharmaceutical quality control and synthesis process control for diagnostic as well as therapeutic radionuclides such as 225Ac, 211At, 90Y or 177Lu.
Alpha-emitter TLC Analysis:
The AR-2000 allows for direct detection of alpha particles from radionuclides like 225Ac, 223Ra, 227Th and 211At instead of direct or indirect decay photons.
Pharmaceutical metabolite analysis:
Radioisotope flexibility and manual or automatic peak analysis for low or high activity products, using beta (3H, 14C), gamma or positron-labeled compounds.
Radiotracer toxicology studies:
High sensitivity for quantitative measurement of 14C-labeled organic compounds and agrichemicals.
Lipid biosynthesis / Lipid analysis:
1D and 2D analysis of complex lipids, phospholipids and glycolipids by TLC with no cutting, scraping or transfer for fast quantitative results.
Radiolabeled reporter gene or enzyme assays:
Simplifies the analysis and improves accuracy for traditional radioisotopic CAT or enzymatic conversion assays using TLC.
Quantitative biochemical separations and planar samples using radiolabeled compounds:
Programmable scanning and quick-change magnetic collimators for resolution and sensitivity optimization.
